Journal of Investigative Dermatology

ORIGINAL ARTICLE

Early life antibiotic exposure causes intestinal dysbiosis and exacerbates skin and lung pathology in experimental systemic sclerosis FREE

: Using a mouse model of systemic scleroderma, Mehta and colleagues found that prenatal or perinatal streptomycin treatment induced intestinal dysbiosis, modified the microbiota long-term, aggravated skin pathology, and accelerated lung fibrosis, suggesting that intestinal dysbiosis early in life increases the risk of autoimmune dysfunction later in life. To learn more about the techniques used in this paper, visit this Research Techniques Made Simple article

ORIGINAL ARTICLE

Dermal Blimp1 acts downstream of epidermal TGFβ and Wnt/β-catenin to regulate hair follicle formation and growth FREE

Telerman and colleagues described a critical role for the transcription factor Blimp1, which is known to be involved in regulating differentiation in multiple cell types, in dermal papilla signaling and hair follicle initiation and regeneration in mice. To learn more about the techniques used in this paper, visit this Research Techniques Made Simple article

ORIGINAL ARTICLE

Pivotal Role of Lesional and Perilesional T/B Lymphocytes in Pemphigus Pathogenesis FREE

Yuan and colleagues reported that lesions of pemphigus patients contained antigen-specific B cells that were capable of producing autoantibodies, interleukin-21/17-producing T cells, and IgG+ plasma cells, supporting an important function of these infiltrating lymphocytes in concert with previously implicated autoantibodies in acantholysis in pemphigus pathogenesis. To learn more about the techniques used in this paper, visit these Research Techniques Made Simple articles on flow cytometry, Elisa, and Elispot.

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Keratinocyte Sonic Hedgehog Up-regulation Drives the Development of Giant Congenital Nevi via Paracrine Endothelin-1 Secretion

Arash Chitsazan, Blake Ferguson, Rehan Villani, Herlina Y. Handoko, Pamela Mukhopadhyay, Brian Gabrielli, Wolter J. Mooi, H. Peter Soyer, Duncan Lambie, Kiarash Khosrotehrani, Grant Morahan, Graeme J. Walker

DOI: http://dx.doi.org/10.1016/j.jid.2017.10.032

Publication stage: In Press Accepted Manuscript

Journal of Investigative Dermatology

Published online: November 11, 2017

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Recessive mutation in FAM83G associated with palmoplantar keratoderma and exuberant scalp hair

Thiviyani Maruthappu, Lisa A. McGinty, Diana C. Blaydon, Benjamin Fell, Arto Määttä, Rebecca Duit, Tim Hawkins, Kristin M. Braun, Michael A. Simpson, Edel A. O’Toole, David P. Kelsell

DOI: http://dx.doi.org/10.1016/j.jid.2017.10.031

Publication stage: In Press Accepted Manuscript

Journal of Investigative Dermatology

Published online: November 11, 2017

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Hidradenitis suppurativa-like lesions associated with pharmacologic inhibition of gamma-secretase

Geraldine O’Sullivan Coyne, Therese S. Woodring, Chyi-Chia R. Lee, Alice P. Chen, Heidi H. Kong

DOI: http://dx.doi.org/10.1016/j.jid.2017.09.051

Publication stage: In Press Accepted Manuscript

Journal of Investigative Dermatology

Published online: November 11, 2017

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Merkel cells sense cooling with TRPM8 channels

Valentine Bouvier, Yann Roudaut, Nancy Osorio, Jean-Marc Aimonetti, Edith Ribot-Ciscar, Virginie Penalba, Thierry Merrot, Nicolas Lebonvallet, Christelle Le Gall-Ianotto, Laurent Misery, Patrick Delmas, Marcel Crest

DOI: http://dx.doi.org/10.1016/j.jid.2017.11.004

Publication stage: In Press Accepted Manuscript

Journal of Investigative Dermatology

Published online: November 11, 2017

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Intra- and interfamilial phenotype variability associated with mutations in γ-secretase subunit-encoding PSENEN

Jorge Frank, Damian J. Ralser, Regina C. Betz

DOI: http://dx.doi.org/10.1016/j.jid.2017.09.050

Publication stage: In Press Accepted Manuscript

Journal of Investigative Dermatology

Published online: November 11, 2017

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Subcellular Selective Photothermolysis of Melanosomes in Adult Zebrafish Skin Following 1064-nm Q-Switched Nd:YAG Laser Irradiation

Jae Hwan Kim, Ho Kim, Hae Chul Park, Il-Hwan Kim

DOI: http://dx.doi.org/10.1038/jid.2010.129

Journal of Investigative Dermatology, Vol. 130, Issue 9

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Dermal Blimp1 Acts Downstream of Epidermal TGFβ and Wnt/β-Catenin to Regulate Hair Follicle Formation and Growth

Stephanie B. Telerman, Emanuel Rognoni, Inês Sequeira, Angela Oliveira Pisco, Beate M. Lichtenberger, Oliver J. Culley, Priyalakshmi Viswanathan, Ryan R. Driskell, Fiona M. Watt

DOI: http://dx.doi.org/10.1016/j.jid.2017.06.015

Journal of Investigative Dermatology, Vol. 137, Issue 11

Open Access

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Oral Vitamin D Rapidly Attenuates Inflammation from Sunburn: An Interventional Study

Jeffrey F. Scott, Lopa M. Das, Sayeeda Ahsanuddin, Yuqi Qiu, Amy M. Binko, Zachary P. Traylor, Sara M. Debanne, Kevin D. Cooper, Rebecca Boxer, Kurt Q. Lu

DOI: http://dx.doi.org/10.1016/j.jid.2017.04.040

Journal of Investigative Dermatology, Vol. 137, Issue 10

Open Access

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Cyclosporine Use in Epidermal Necrolysis Is Associated with an Important Mortality Reduction: Evidence from Three Different Approaches

Carlos González-Herrada, Sara Rodríguez-Martín, Lucía Cachafeiro, Victoria Lerma, Olga González, José A. Lorente, Antonio Rodríguez-Miguel, Jessica González-Ramos, Gaston Roustan, Elena Ramírez, Teresa Bellón, Francisco J. de Abajo for the PIELenRed Therapeutic Management Working Group

DOI: http://dx.doi.org/10.1016/j.jid.2017.05.022

Journal of Investigative Dermatology, Vol. 137, Issue 10

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Early-Life Antibiotic Exposure Causes Intestinal Dysbiosis and Exacerbates Skin and Lung Pathology in Experimental Systemic Sclerosis

Heena Mehta, Philippe-Olivier Goulet, Shunya Mashiko, Jade Desjardins, Gemma Pérez, Martial Koenig, Jean-Luc Senécal, Marco Constante, Manuela M. Santos, Marika Sarfati

DOI: http://dx.doi.org/10.1016/j.jid.2017.06.019

Journal of Investigative Dermatology, Vol. 137, Issue 11

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November 2017

Volume 137, Issue 11

November 2017
Volume 137, Issue 11

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This Month's Highlights

Keratinocyte Sonic Hedgehog Up-regulation Drives the Development of Giant Congenital Nevi via Paracrine Endothelin-1 Secretion

Recessive mutation in FAM83G associated with palmoplantar keratoderma and exuberant scalp hair

Hidradenitis suppurativa-like lesions associated with pharmacologic inhibition of gamma-secretase

Merkel cells sense cooling with TRPM8 channels

Intra- and interfamilial phenotype variability associated with mutations in γ-secretase subunit-encoding PSENEN

Most Downloaded JID Articles Published Since 2014

Subcellular Selective Photothermolysis of Melanosomes in Adult Zebrafish Skin Following 1064-nm Q-Switched Nd:YAG Laser Irradiation

Dermal Blimp1 Acts Downstream of Epidermal TGFβ and Wnt/β-Catenin to Regulate Hair Follicle Formation and Growth

Oral Vitamin D Rapidly Attenuates Inflammation from Sunburn: An Interventional Study

Cyclosporine Use in Epidermal Necrolysis Is Associated with an Important Mortality Reduction: Evidence from Three Different Approaches

Early-Life Antibiotic Exposure Causes Intestinal Dysbiosis and Exacerbates Skin and Lung Pathology in Experimental Systemic Sclerosis

Developing biomarkers for predicting clinical relapse in pemphigus patients treated with rituximab

Precise role of dermal fibroblasts on melanocyte pigmentation

JID Connector

Research Techniques Made Simple: Methodology and Applications of Förster Resonance Energy Transfer (FRET) Microscopy

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JID Author Corner

ESDR 2017 Supplement

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This Month's Highlights

Keratinocyte Sonic Hedgehog Up-regulation Drives the Development of Giant Congenital Nevi via Paracrine Endothelin-1 Secretion

Recessive mutation in FAM83G associated with palmoplantar keratoderma and exuberant scalp hair

Hidradenitis suppurativa-like lesions associated with pharmacologic inhibition of gamma-secretase

Merkel cells sense cooling with TRPM8 channels

Intra- and interfamilial phenotype variability associated with mutations in γ-secretase subunit-encoding PSENEN

Most Downloaded JID Articles Published Since 2014

Subcellular Selective Photothermolysis of Melanosomes in Adult Zebrafish Skin Following 1064-nm Q-Switched Nd:YAG Laser Irradiation

Dermal Blimp1 Acts Downstream of Epidermal TGFβ and Wnt/β-Catenin to Regulate Hair Follicle Formation and Growth

Oral Vitamin D Rapidly Attenuates Inflammation from Sunburn: An Interventional Study

Cyclosporine Use in Epidermal Necrolysis Is Associated with an Important Mortality Reduction: Evidence from Three Different Approaches

Early-Life Antibiotic Exposure Causes Intestinal Dysbiosis and Exacerbates Skin and Lung Pathology in Experimental Systemic Sclerosis

Developing biomarkers for predicting clinical relapse in pemphigus patients treated with rituximab

Precise role of dermal fibroblasts on melanocyte pigmentation

JID Connector

Research Techniques Made Simple: Methodology and Applications of Förster Resonance Energy Transfer (FRET) Microscopy

Current Issue

Journal Metrics

JID Author Corner

ESDR 2017 Supplement

List of Issues

Publishing Partners