Journal of Investigative Dermatology

ORIGINAL ARTICLE

High fat diet exacerbates early psoriatic skin inflammation independent of obesity: Saturated fatty acids as key players FREE

While an association between obesity and psoriasis (and other chronic inflammatory diseases) has been documented previously, Herbert and colleagues show that the serum level of free fatty acids, rather than obesity, is related to psoriasiform inflammation. In addition, manipulation of dietary saturated fatty acids modulated inflammation in a mouse model. To learn more about the techniques used in this paper, visit the Research Techniques Made Simple article on mouse models of psoriasis and ELISA here and here.

ORIGINAL ARTICLE

CARD14 gain-of-function mutation alone is sufficient to drive IL-23/IL-17-mediated psoriasiform skin inflammation in vivo FREE

Shedding light on the molecular pathogenesis of psoriasis, Mellett and colleagues report that a CARD14 gain-of-function mutation, which has been identified as an autosomal dominant mutation associated with increased susceptibility to psoriasis, is sufficient to induce a chronic psoriatic phenotype driven by the interleukin-23/17 axis in mice. To learn more about the techniques used in this paper, visit the Research Techniques Made Simple article on RNAseq .

ORIGINAL ARTICLE

Biosynthesis of D-series resolvins in skin provides insights into their role in tissue repair. FREE

After identifying the D-series resolvins in skin after injury via a metabolomics approach, Hellman and colleagues report that topical application of these lipid mediators facilitates re-epithelialization and enhances migration of epidermal keratinocytes in wounded skin, indicating a functional role for resolvins in tissue repair.

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Is CCR6 required for the development of psoriasiform dermatitis in mice?

Sebastian Yu, Xuesong Wu, Yan Zhou, Dan Han, Leif S. Anderson, Scott I. Simon, Samuel T. Hwang, Yasutomo Imai

DOI: https://doi.org/10.1016/j.jid.2018.07.036

Publication stage: In Press Accepted Manuscript

Journal of Investigative Dermatology

Published online: September 4, 2018

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IFN-γ promotes but dexamethasone dissociates TLR2/1-induced host responses in human macrophages

Philipp Kröll, Kristin Knoke, Julia Steiger, Mario Fabri

DOI: https://doi.org/10.1016/j.jid.2018.07.035

Publication stage: In Press Accepted Manuscript

Journal of Investigative Dermatology

Published online: September 4, 2018

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Age-dependent transformation of skin biomechanical properties and micromorphology during infancy and childhood

Joachim W. Fluhr, Gaëlle Bellemère, Chiara Ferrari, Clarence De Belilovsky, Gaëtan Boyer, Nadège Lachmann, Colin P. McGuckin, Nico Forraz, Razvigor Darlenski, Bernard Chadoutaud, Philippe Msika, Caroline Baudouin, Giovanni Pellacani

DOI: https://doi.org/10.1016/j.jid.2018.07.034

Publication stage: In Press Accepted Manuscript

Journal of Investigative Dermatology

Published online: September 1, 2018

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Lineage identity and location within the dermis determine the function of papillary and reticular fibroblasts in human skin

Ana Korosec, Sophie Frech, Bernhard Gesslbauer, Martin Vierhapper, Christine Radtke, Peter Petzelbauer, Beate M. Lichtenberger

DOI: https://doi.org/10.1016/j.jid.2018.07.033

Publication stage: In Press Accepted Manuscript

Journal of Investigative Dermatology

Published online: September 1, 2018

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IL-22 downregulates Cx43 expression and decreases gap junctional intercellular communication by activating the JNK pathway in psoriasis

Jingyao Liang, Pingjiao Chen, Changxing Li, Dongmei Li, Jianqin Wang, Rujun Xue, Sanquan Zhang, Jianbo Ruan, Xibao Zhang

DOI: https://doi.org/10.1016/j.jid.2018.07.032

Publication stage: In Press Accepted Manuscript

Journal of Investigative Dermatology

Published online: August 29, 2018

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The Anti-Inflammatory Activities of Propionibacterium acnes CAMP Factor-Targeted Acne Vaccines

Yanhan Wang, Tissa R. Hata, Yun Larry Tong, Ming-Shan Kao, Christos C. Zouboulis, Richard L. Gallo, Chun-Ming Huang

DOI: https://doi.org/10.1016/j.jid.2018.05.032

Publication stage: In Press Corrected Proof

Journal of Investigative Dermatology

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Vaccinating against Acne: Benefits and Potential Pitfalls

Emmanuel Contassot

DOI: https://doi.org/10.1016/j.jid.2018.06.177

Publication stage: In Press Corrected Proof

Journal of Investigative Dermatology

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High-Fat Diet Exacerbates Early Psoriatic Skin Inflammation Independent of Obesity: Saturated Fatty Acids as Key Players

Diana Herbert, Sandra Franz, Yulia Popkova, Ulf Anderegg, Jürgen Schiller, Katharina Schwede, Axel Lorz, Jan C. Simon, Anja Saalbach

DOI: https://doi.org/10.1016/j.jid.2018.03.1522

Journal of Investigative Dermatology, Vol. 138, Issue 9

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Filaggrin 2 Deficiency Results in Abnormal Cell-Cell Adhesion in the Cornified Cell Layers and Causes Peeling Skin Syndrome Type A

Janan Mohamad, Ofer Sarig, Lisa M. Godsel, Alon Peled, Natalia Malchin, Ron Bochner, Dan Vodo, Tom Rabinowitz, Mor Pavlovsky, Shahar Taiber, Maya Fried, Marina Eskin-Schwartz, Siwar Assi, Noam Shomron, Jouni Uitto, Jennifer L. Koetsier, Reuven Bergman, Kathleen J. Green, Eli Sprecher

DOI: https://doi.org/10.1016/j.jid.2018.04.032

Journal of Investigative Dermatology, Vol. 138, Issue 8

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Risk of Skin Cancer Associated with the Use of UV Nail Lamp

Alina Markova, Martin A. Weinstock

DOI: https://doi.org/10.1038/jid.2012.440

Journal of Investigative Dermatology, Vol. 133, Issue 4

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September 2018

Volume 138, Issue 9

September 2018
Volume 138, Issue 9

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This Month's Highlights

Is CCR6 required for the development of psoriasiform dermatitis in mice?

IFN-γ promotes but dexamethasone dissociates TLR2/1-induced host responses in human macrophages

Age-dependent transformation of skin biomechanical properties and micromorphology during infancy and childhood

Lineage identity and location within the dermis determine the function of papillary and reticular fibroblasts in human skin

IL-22 downregulates Cx43 expression and decreases gap junctional intercellular communication by activating the JNK pathway in psoriasis

Most Downloaded JID Articles Published Since 2014

The Anti-Inflammatory Activities of Propionibacterium acnes CAMP Factor-Targeted Acne Vaccines

Vaccinating against Acne: Benefits and Potential Pitfalls

High-Fat Diet Exacerbates Early Psoriatic Skin Inflammation Independent of Obesity: Saturated Fatty Acids as Key Players

Filaggrin 2 Deficiency Results in Abnormal Cell-Cell Adhesion in the Cornified Cell Layers and Causes Peeling Skin Syndrome Type A

Risk of Skin Cancer Associated with the Use of UV Nail Lamp

The spectrum of manifestations in desmoplakin gene (DSP) spectrin repeat 6 domain mutations: Immunophenotyping and response to ustekinumab

Establishment of integration-free induced pluripotent stem cells from human recessive dystrophic epidermolysis bullosa keratinocytes

JID Connector

Research Techniques Made Simple: Sample Size Estimation and Power Calculation

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Journal Metrics

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JID Author Corner

IID 2018 Supplement

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This Month's Highlights

Is CCR6 required for the development of psoriasiform dermatitis in mice?

IFN-γ promotes but dexamethasone dissociates TLR2/1-induced host responses in human macrophages

Age-dependent transformation of skin biomechanical properties and micromorphology during infancy and childhood

Lineage identity and location within the dermis determine the function of papillary and reticular fibroblasts in human skin

IL-22 downregulates Cx43 expression and decreases gap junctional intercellular communication by activating the JNK pathway in psoriasis

Most Downloaded JID Articles Published Since 2014

The Anti-Inflammatory Activities of Propionibacterium acnes CAMP Factor-Targeted Acne Vaccines

Vaccinating against Acne: Benefits and Potential Pitfalls

High-Fat Diet Exacerbates Early Psoriatic Skin Inflammation Independent of Obesity: Saturated Fatty Acids as Key Players

Filaggrin 2 Deficiency Results in Abnormal Cell-Cell Adhesion in the Cornified Cell Layers and Causes Peeling Skin Syndrome Type A

Risk of Skin Cancer Associated with the Use of UV Nail Lamp

The spectrum of manifestations in desmoplakin gene (DSP) spectrin repeat 6 domain mutations: Immunophenotyping and response to ustekinumab

Establishment of integration-free induced pluripotent stem cells from human recessive dystrophic epidermolysis bullosa keratinocytes

JID Connector

Research Techniques Made Simple: Sample Size Estimation and Power Calculation

Current Issue

Journal Metrics

List of Issues

JID Author Corner

IID 2018 Supplement

Publishing Partners