Home Page: Journal of Investigative Dermatology

ORIGINAL ARTICLE

TERT, BRAF, and NRAS mutational heterogeneity between paired primary and metastatic melanoma tumors FREE

Using multiple molecular sequencing methods, Chang et al. found heterogeneity in the presence of BRAF^V600, NRAS^Q61, TERT^124C>T, and TERT^146C>T mutations in paired primary and metastatic tumors or multiple metastatic tumors from 18 of 99 (18%) patients with melanoma. These results suggest that differing mutational profiles occur in primary melanomas from the same individual and that this information is integral to treatment response and disease outcomes. .

ORIGINAL ARTICLE

Identification of a human skin commensal bacterium that selectively kills Cutibacterium acnes FREE

O'Neill et al. describe antimicrobial peptides that are secreted by the skin-resident commensal Staphylococcus capitis E12 and selectively inhibit growth of the acne vulgaris pathogen Cutiebacterium acnes, highlighting the potential for identification of novel antibacterial agents for treatment of skin diseases from the skin microbiome. To learn more about the techniques used in this paper, visit the Research Techniques Made Simple article.

ORIGINAL ARTICLE

PAR2 mediates itch via TRPV3 signaling in keratinocytes FREE

Zhao et al. report that in keratinocytes, TRPV3 and PAR2, which are upregulated in skin of patients with atopic dermatitis, function together as part of a signaling cascade to convey itch, indicating that targeting of either of these components may provide a potential antipruritic therapy for atopic dermatitis. To learn more about the techniques used in this paper, visit this Research Techniques Made Simple article.

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Cancer-Associated Fibroblasts in Mycosis Fungoides Promote Tumor Cell Migration and Drug Resistance via CXCL12/CXCR4

Anna Aronovich, Lilach Moyal, Batia Gorovitz, Iris Amitay-Laish, Hadas Prag Naveh, Yaara Forer, Lea Maron, Jamal Knaneh, Dean Ad-El, Dafna Yaacobi, Eric Barel, Neta Erez, Emmilia Hodak

DOI: https://doi.org/10.1016/j.jid.2020.06.034

Publication stage: In Press Journal Pre-Proof

Journal of Investigative Dermatology

Published online: August 11, 2020

Genotype-Phenotype Correlation of TRPV3-Related Olmsted Syndrome

Weilong Zhong, Linghan Hu, Xu Cao, Jiahui Zhao, Xianning Zhang, Mingyang Lee, Huijun Wang, Jie Zhang, Quan Chen, Cheng Feng, Lina Duo, Xiuli Wang, Li Tang, Zhimiao Lin, Yong Yang

DOI: https://doi.org/10.1016/j.jid.2020.06.035

Publication stage: In Press Journal Pre-Proof

Journal of Investigative Dermatology

Published online: August 10, 2020

Germline mutation of PLCD1 contributes to human multiple pilomatricomas via PKD/ERK_1/2 cascade and TRPV6

Kai Liu, Junyu Luo, Tingbin Ma, Muping Fang, Zhe Xu, Li Wang, Xiang Yang Zhang, Jingmin Wen, Chunjie Liu, Yanjie Cao, Xiunan Li, Luoying Zhang, Anyuan Guo, Ning Wang, Ping Yi, Jing Yu Liu

DOI: https://doi.org/10.1016/j.jid.2020.05.121

Publication stage: In Press Journal Pre-Proof

Journal of Investigative Dermatology

Published online: August 10, 2020

Distribution and functional consequences of somatic MAP2K1 mutations in affected skin associated with bone lesions in melorheostosis

Smita Jha, Aleksandra Ivovic, Heeseog Kang, Françoise Meylan, Eric P. Hanson, Casey Rimland, Eileen Lange, James Katz, Alison McBride, Andrew C. Warner, Elijah F. Edmondson, Edward W. Cowen, Joan C. Marini, Richard M. Siegel, Timothy Bhattacharyya

DOI: https://doi.org/10.1016/j.jid.2020.06.036

Publication stage: In Press Journal Pre-Proof

Journal of Investigative Dermatology

Published online: August 10, 2020

CLINICAL RELEVANCE OF POLYMORPHONUCLEAR MYELOID-DERIVED SUPPRESSOR CELLS (PMN-MDSC) IN AUTOIMMUNE BLISTERING DISORDERS PEMPHIGUS VULGARIS AND BULLOUS PEMPHIGOID

Ayse Oktem, Utku Horzum, Pelin Ertop, Nihal Kundakci, Bengu Nisa Akay, Basak Yalcin, Gunes Esendagli

DOI: https://doi.org/10.1016/j.jid.2020.07.015

Publication stage: In Press Journal Pre-Proof

Journal of Investigative Dermatology

Published online: August 9, 2020

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Propionibacterium acnes Strain Populations in the Human Skin Microbiome Associated with Acne

Sorel Fitz-Gibbon, Shuta Tomida, Bor-Han Chiu, Lin Nguyen, Christine Du, Minghsun Liu, David Elashoff, Marie C. Erfe, Anya Loncaric, Jenny Kim, Robert L. Modlin, Jeff F. Miller, Erica Sodergren, Noah Craft, George M. Weinstock, Huiying Li

DOI: https://doi.org/10.1038/jid.2013.21

Journal of Investigative Dermatology, Vol. 133, Issue 9

Open Archive

Author Index

DOI: https://doi.org/10.1016/j.jid.2018.03.1494

Journal of Investigative Dermatology, Vol. 138, Issue 5

Open Archive

Research Techniques Made Simple: Optical Clearing and Three-Dimensional Volumetric Imaging of Skin Biopsies

Yingrou Tan, Carolyn Pei Lyn Chiam, Yuning Zhang, Hong Liang Tey, Lai Guan Ng

DOI: https://doi.org/10.1016/j.jid.2020.04.014

Journal of Investigative Dermatology, Vol. 140, Issue 7

IL-36 Promotes Systemic IFN-I Responses in Severe Forms of Psoriasis

Marika Catapano, Marta Vergnano, Marco Romano, Satveer K. Mahil, Siew-Eng Choon, A. David Burden, Helen S. Young, Ian M. Carr, Helen J. Lachmann, Giovanna Lombardi, Catherine H. Smith, Francesca D. Ciccarelli, Jonathan N. Barker, Francesca Capon

DOI: https://doi.org/10.1016/j.jid.2019.08.444

Journal of Investigative Dermatology, Vol. 140, Issue 4

Open Access

773 Generation of human hair follicle organoids in vitro and ex vivo by co-culture of primary human hair matrix keratinocytes and dermal papilla fibroblasts

I. Piccini, K. Bakkar, C. Collin-Djangoné, J. Gherardini, R. Paus, M. Bertolini

DOI: https://doi.org/10.1016/j.jid.2020.03.787

Journal of Investigative Dermatology, Vol. 140, Issue 7

August 2020

Volume 140, Issue 8

August 2020
Volume 140, Issue 8

JID invites submission of reports in the field of aging for a Special Issue on Aging. Areas of interest include senescence, regeneration, life span, DNA damage and repair, telomeres, calorie restriction, longevity, mitotic ageing rate, and stem cells. Manuscript deadline: September 1, 2020. Contact the Editor at JIDEditor@sidnet.org for submission details. For additional details, please see the full announcement.

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Research Techniques Made Simple: Mouse Bacterial Skin Infection Models for Immunity Research

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Cancer-Associated Fibroblasts in Mycosis Fungoides Promote Tumor Cell Migration and Drug Resistance via CXCL12/CXCR4

Genotype-Phenotype Correlation of TRPV3-Related Olmsted Syndrome

Germline mutation of PLCD1 contributes to human multiple pilomatricomas via PKD/ERK_1/2 cascade and TRPV6

Distribution and functional consequences of somatic MAP2K1 mutations in affected skin associated with bone lesions in melorheostosis

CLINICAL RELEVANCE OF POLYMORPHONUCLEAR MYELOID-DERIVED SUPPRESSOR CELLS (PMN-MDSC) IN AUTOIMMUNE BLISTERING DISORDERS PEMPHIGUS VULGARIS AND BULLOUS PEMPHIGOID

Most Downloaded JID Articles Published Since 2014

Propionibacterium acnes Strain Populations in the Human Skin Microbiome Associated with Acne

Author Index

Research Techniques Made Simple: Optical Clearing and Three-Dimensional Volumetric Imaging of Skin Biopsies

IL-36 Promotes Systemic IFN-I Responses in Severe Forms of Psoriasis

773 Generation of human hair follicle organoids in vitro and ex vivo by co-culture of primary human hair matrix keratinocytes and dermal papilla fibroblasts

The spectrum of manifestations in desmoplakin gene (DSP) spectrin repeat 6 domain mutations: Immunophenotyping and response to ustekinumab

Establishment of integration-free induced pluripotent stem cells from human recessive dystrophic epidermolysis bullosa keratinocytes

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