Home Page: Journal of Investigative Dermatology

ORIGINAL ARTICLE

TERT, BRAF, and NRAS mutational heterogeneity between paired primary and metastatic melanoma tumors FREE

Using multiple molecular sequencing methods, Chang et al. found heterogeneity in the presence of BRAF^V600, NRAS^Q61, TERT^124C>T, and TERT^146C>T mutations in paired primary and metastatic tumors or multiple metastatic tumors from 18 of 99 (18%) patients with melanoma. These results suggest that differing mutational profiles occur in primary melanomas from the same individual and that this information is integral to treatment response and disease outcomes. .

ORIGINAL ARTICLE

Identification of a human skin commensal bacterium that selectively kills Cutibacterium acnes FREE

O'Neill et al. describe antimicrobial peptides that are secreted by the skin-resident commensal Staphylococcus capitis E12 and selectively inhibit growth of the acne vulgaris pathogen Cutiebacterium acnes, highlighting the potential for identification of novel antibacterial agents for treatment of skin diseases from the skin microbiome. To learn more about the techniques used in this paper, visit the Research Techniques Made Simple article.

ORIGINAL ARTICLE

PAR2 mediates itch via TRPV3 signaling in keratinocytes FREE

Zhao et al. report that in keratinocytes, TRPV3 and PAR2, which are upregulated in skin of patients with atopic dermatitis, function together as part of a signaling cascade to convey itch, indicating that targeting of either of these components may provide a potential antipruritic therapy for atopic dermatitis. To learn more about the techniques used in this paper, visit this Research Techniques Made Simple article.

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MELANOCYTE PRECURSORS IN THE HAIR FOLLICLE BULGE OF REPIGMENTED VITILIGO SKIN ARE CONTROLLED BY RHO-GTPase, KCTD10 AND CTNNB1 SIGNALING

Nathaniel B. Goldstein, Andrea Steel, Chauncey C. Barbulescu, Maranke I. Koster, Michael J. Wright, Kenneth L. Jones, Bifeng Gao, Brian Ward, Brian Woessner, Zachary Trottier, Jen Pakieser, Junxiao Hu, Karoline A. Lambert, Yiqun G. Shellman, Mayumi Fujita, William A. Robinson, Dennis R. Roop, David A. Norris, Stanca A. Birlea

DOI: https://doi.org/10.1016/j.jid.2020.07.016

Publication stage: In Press Journal Pre-Proof

Journal of Investigative Dermatology

Published online: August 12, 2020

PAR2, keratinocytes and cathepsin S mediate the sensory effects of ciguatoxins responsible for ciguatera poisoning

Killian L’Herondelle, Ophelie Pierre, Sophie Fouyet, Raphael Leschiera, Christelle Le gall-ianotto, Reginald Philippe, Paul Buscaglia, Olivier Mignen, Matthieu Talagas, Richard J. Lewis, Laurence Michel, Laurent Misery, Raphaele Le garrec

DOI: https://doi.org/10.1016/j.jid.2020.07.020

Publication stage: In Press Journal Pre-Proof

Journal of Investigative Dermatology

Published online: August 12, 2020

Dermal Fibroblast CCN1 Expression in Mice Recapitulates Human Skin Dermal Aging

Taihao Quan, Yaping Xiang, Yingchun Liu, Zhaoping Qin, Yan Yang, George Bou-Gharios, John J. Voorhees, Andrzej A. Dlugosz, Gary J. Fisher

DOI: https://doi.org/10.1016/j.jid.2020.07.019

Publication stage: In Press Journal Pre-Proof

Journal of Investigative Dermatology

Published online: August 12, 2020

The distinctive genomic landscape of giant congenital melanocytic nevi

Mitchell S. Stark, Gemma Tell-Martí, Vanessa Martins da Silva, Estefania Martinez-Barrios, Neus Calbet-Llopart, Asunción Vicente, Richard A. Sturm, H. Peter Soyer, Susana Puig, Josep Malvehy, Cristina Carrera, Joan A. Puig-Butillé

DOI: https://doi.org/10.1016/j.jid.2020.07.022

Publication stage: In Press Journal Pre-Proof

Journal of Investigative Dermatology

Published online: August 12, 2020

Cancer-Associated Fibroblasts in Mycosis Fungoides Promote Tumor Cell Migration and Drug Resistance via CXCL12/CXCR4

Anna Aronovich, Lilach Moyal, Batia Gorovitz, Iris Amitay-Laish, Hadas Prag Naveh, Yaara Forer, Lea Maron, Jamal Knaneh, Dean Ad-El, Dafna Yaacobi, Eric Barel, Neta Erez, Emmilia Hodak

DOI: https://doi.org/10.1016/j.jid.2020.06.034

Publication stage: In Press Journal Pre-Proof

Journal of Investigative Dermatology

Published online: August 11, 2020

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Propionibacterium acnes Strain Populations in the Human Skin Microbiome Associated with Acne

Sorel Fitz-Gibbon, Shuta Tomida, Bor-Han Chiu, Lin Nguyen, Christine Du, Minghsun Liu, David Elashoff, Marie C. Erfe, Anya Loncaric, Jenny Kim, Robert L. Modlin, Jeff F. Miller, Erica Sodergren, Noah Craft, George M. Weinstock, Huiying Li

DOI: https://doi.org/10.1038/jid.2013.21

Journal of Investigative Dermatology, Vol. 133, Issue 9

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Author Index

DOI: https://doi.org/10.1016/j.jid.2018.03.1494

Journal of Investigative Dermatology, Vol. 138, Issue 5

Open Archive

IL-36 Promotes Systemic IFN-I Responses in Severe Forms of Psoriasis

Marika Catapano, Marta Vergnano, Marco Romano, Satveer K. Mahil, Siew-Eng Choon, A. David Burden, Helen S. Young, Ian M. Carr, Helen J. Lachmann, Giovanna Lombardi, Catherine H. Smith, Francesca D. Ciccarelli, Jonathan N. Barker, Francesca Capon

DOI: https://doi.org/10.1016/j.jid.2019.08.444

Journal of Investigative Dermatology, Vol. 140, Issue 4

Open Access

Research Techniques Made Simple: Optical Clearing and Three-Dimensional Volumetric Imaging of Skin Biopsies

Yingrou Tan, Carolyn Pei Lyn Chiam, Yuning Zhang, Hong Liang Tey, Lai Guan Ng

DOI: https://doi.org/10.1016/j.jid.2020.04.014

Journal of Investigative Dermatology, Vol. 140, Issue 7

773 Generation of human hair follicle organoids in vitro and ex vivo by co-culture of primary human hair matrix keratinocytes and dermal papilla fibroblasts

I. Piccini, K. Bakkar, C. Collin-Djangoné, J. Gherardini, R. Paus, M. Bertolini

DOI: https://doi.org/10.1016/j.jid.2020.03.787

Journal of Investigative Dermatology, Vol. 140, Issue 7

September 2020

Volume 140, Issue 9

September 2020
Volume 140, Issue 9

JID invites submission of reports in the field of aging for a Special Issue on Aging. Areas of interest include senescence, regeneration, life span, DNA damage and repair, telomeres, calorie restriction, longevity, mitotic ageing rate, and stem cells. Manuscript deadline: September 1, 2020. Contact the Editor at JIDEditor@sidnet.org for submission details. For additional details, please see the full announcement.

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Research Techniques Made Simple: Mouse Bacterial Skin Infection Models for Immunity Research

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MELANOCYTE PRECURSORS IN THE HAIR FOLLICLE BULGE OF REPIGMENTED VITILIGO SKIN ARE CONTROLLED BY RHO-GTPase, KCTD10 AND CTNNB1 SIGNALING

PAR2, keratinocytes and cathepsin S mediate the sensory effects of ciguatoxins responsible for ciguatera poisoning

Dermal Fibroblast CCN1 Expression in Mice Recapitulates Human Skin Dermal Aging

The distinctive genomic landscape of giant congenital melanocytic nevi

Cancer-Associated Fibroblasts in Mycosis Fungoides Promote Tumor Cell Migration and Drug Resistance via CXCL12/CXCR4

Most Downloaded JID Articles Published Since 2014

Propionibacterium acnes Strain Populations in the Human Skin Microbiome Associated with Acne

Author Index

IL-36 Promotes Systemic IFN-I Responses in Severe Forms of Psoriasis

Research Techniques Made Simple: Optical Clearing and Three-Dimensional Volumetric Imaging of Skin Biopsies

773 Generation of human hair follicle organoids in vitro and ex vivo by co-culture of primary human hair matrix keratinocytes and dermal papilla fibroblasts

The spectrum of manifestations in desmoplakin gene (DSP) spectrin repeat 6 domain mutations: Immunophenotyping and response to ustekinumab

Establishment of integration-free induced pluripotent stem cells from human recessive dystrophic epidermolysis bullosa keratinocytes

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