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This Month's Highlights

Czarnowicki and colleagues report increased systemic T cell activation in patients with orphan forms of ichthyosis, rare skin disorders with immune and barrier aberrations. Poor clinical measures also correlated with increased interleukin-17- and interleukin-22-producing T cells in blood samples from these patients, highlighting the potential for systemic therapeutic approaches. To learn more about the techniques used in this paper, visit the Research Techniques Made Simple article on Flow Cytometry.
SanMiguel and colleagues describe short-term perturbations in resident microbial communities following treatment of skin with antiseptic agents commonly used in clinical settings to prevent infection. These shifts are both personalized and body site-specific and primarily affect low-abundance species. To learn more about the techniques used in this paper, visit theResearch Techniques Made Simple article on Ribosomal Sequencing .
Williams and colleagues demonstrate that poor wound healing is associated with increased expression of the NOD2 pattern recognition receptor. NOD2 activation results in delayed wound healing and heightened inflammation, including upregulation of Β-defensins, shedding light on the interplay of the innate immune system and skin microbiota in chronic wound repair. To learn more about the techniques used in this paper, visit the Research Techniques Made Simple articles on Cell Migration using Wound Healing Assay
    • Mutations in PERP cause dominant and recessive keratoderma

      Sabine Duchatelet, Lynn M. Boyden, Akemi Ishida-Yamamoto, Jing Zhou, Laure Guibbal, Ronghua Hu, Young H. Lim, Christine Bole-Feysot, Patrick Nitschké, Fernando Santos-Simarro, Raul de Lucas, Leonard M. Milstone, Vanessa Gildenstern, Yolanda R. Helfrich, Laura D. Attardi, Richard P. Lifton, Keith A. Choate, Alain Hovnanian
      Publication stage: In Press Accepted Manuscript
      Journal of Investigative Dermatology
      Published online: October 12, 2018
    • Reduced intensity conditioning regimens, prior chronic lymphocytic leukemia, and graft versus host disease are associated with higher rates of skin cancer following allogeneic hematopoietic stem cell transplantation

      Peggy A. Wu, Robert S. Stern, Victor Huang, Kevin X. Liu, Chen (Amy) Chen, Dimitrios Tzachanis, Robin M. Joyce, Roger B. Davis, Vincent T. Ho
      Publication stage: In Press Accepted Manuscript
      Journal of Investigative Dermatology
      Published online: October 11, 2018
    • Influenza Vaccination Rates in Adults with Psoriasis Compared to Adults with Other Chronic Diseases

      Megan H. Noe, Daniel B. Shin, Rebecca A. Hubbard, Sean Hennessy, Joel M. Gelfand
      Publication stage: In Press Accepted Manuscript
      Journal of Investigative Dermatology
      Published online: October 10, 2018
    • Enhancer connectome nominates target genes of inherited risk variants from inflammatory skin disorders

      Mark Y. Jeng, Maxwell R. Mumbach, Jeffrey M. Granja, Ansuman T. Satpathy, Howard Y. Chang, Anne Lynn S. Chang
      Publication stage: In Press Accepted Manuscript
      Journal of Investigative Dermatology
      Published online: October 10, 2018
      Open Access
    • BP180 Autoantibodies Target Different Epitopes in Multiple Sclerosis or Alzheimer’s Disease than in Bullous Pemphigoid

      Jussi Tuusa, Outi Lindgren, Hanna-Mari Tertsunen, Wataru Nishie, Nina Kokkonen, Laura Huilaja, Kentaro Izumi, Sanna-Kaisa Herukka, Jouko Miettunen, Hiroshi Shimizu, Anne M. Remes, Kaisa Tasanen
      Publication stage: In Press Accepted Manuscript
      Journal of Investigative Dermatology
      Published online: October 10, 2018

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30 September 2018:  Bob Dellavalle of the University of Colorado interviews Akiharu Kubo, MD, PhD of Keio University in Tokyo, JSID Annual Lecturer at IID2018.

21 August 2018:  Table of Contents September 2018 issue of the JID

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