QUESTIONS
- What is your diagnosis?
- Eosinophilic fasciitis.
- Progeria.
- Systemic sclerosis.
- Vitiligo.
- Scleroderma.
- Which gene signature patterns are associated with likelihood for improvement in systemic sclerosis?
- Fibroproliferative.
- Inflammatory.
- Limited.
- Normal-like.
- Diffuse.
- Which treatment was shown to lead to clinical and histologic improvement in systemic sclerosis in certain intrinsic gene expression patterns?
- Cyclophosphamide.
- Methotrexate.
- Mycophenolate mofetil.
- Minocycline.
- All of the above.
TOPIC ARTICLE
Questions 2 and 3 refer to the following article:
Answers to the questions are available in the supplementary material online.
- Supplementary Information 1
Supplementary material is available at http://dx.doi.org/10.1038/jid.2013.249
Additional images related to this condition and the differential diagnosis may be found at http://info.visualdx.com/l/11412/2013-03-05/rpvhd.
REFERENCES
- Molecular signatures in skin associated with clinical improvement during mycophenolate treatment in systemic sclerosis.J Invest Dermatol. 2013; 133: 1979-1989
Article info
Footnotes
JID and Logical Images, Inc., have cooperated to offer the JID VisualDx Quiz, incorporating diagnostic images from VisualDx’s vast database. Questions relate to the image as well as to selected articles in JID, which are listed after the questions. Answers will be posted as supplementary material. We hope you enjoy this challenge.
Identification
Copyright
© 2013 The Society for Investigative Dermatology, Inc. Published by Elsevier Inc.
User license
Elsevier user license | How you can reuse 
Elsevier's open access license policy
Elsevier user license
Permitted
For non-commercial purposes:
- Read, print & download
- Text & data mine
- Translate the article
Not Permitted
- Reuse portions or extracts from the article in other works
- Redistribute or republish the final article
- Sell or re-use for commercial purposes
Elsevier's open access license policy
36353-3&id=fx1.jpg){kind=link}