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JID VisualDx Quiz: August 2013

      QUESTIONS

      • What is your diagnosis?
        • Eosinophilic fasciitis.
        • Progeria.
        • Systemic sclerosis.
        • Vitiligo.
        • Scleroderma.
      • Which gene signature patterns are associated with likelihood for improvement in systemic sclerosis?
        • Fibroproliferative.
        • Inflammatory.
        • Limited.
        • Normal-like.
        • Diffuse.
      • Which treatment was shown to lead to clinical and histologic improvement in systemic sclerosis in certain intrinsic gene expression patterns?
        • Cyclophosphamide.
        • Methotrexate.
        • Mycophenolate mofetil.
        • Minocycline.
        • All of the above.

      TOPIC ARTICLE

      Questions 2 and 3 refer to the following article:
      Answers to the questions are available in the supplementary material online.
      Additional images related to this condition and the differential diagnosis may be found at http://info.visualdx.com/l/11412/2013-03-05/rpvhd.

      REFERENCES

        • Hinchcliff M.
        • Huang C.-C.
        • Wood T.A.
        • et al.
        Molecular signatures in skin associated with clinical improvement during mycophenolate treatment in systemic sclerosis.
        J Invest Dermatol. 2013; 133: 1979-1989