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JID VisualDx Quiz: April 2014

      Figure thumbnail fx1
      Image appears with permission from VisualDx. © Logical Images, Inc.

      QUESTIONS

      1. What is your diagnosis?
      • a.
        Nummular dermatitis.
      • b.
        Venous dermatitis.
      • c.
        Xerosis.
      • d.
        Ichthyosis vulgaris.
      • e.
        Tinea corporis.
      2. Which of the following is true of occlusion?
      • a.
        Increased epidermal maturation is seen when occlusion is applied.
      • b.
        Optimal benefits of occlusion are seen quickly.
      • c.
        Scar reduction resulting from occlusion is similar to that achieved with silicone sheets.
      • d.
        The effects of occlusion are mediated by IL-7.
      • e.
        Occlusion increases transepidermal water loss.
      3. Similarities between mucosal healing (compared with cutaneous healing) and healing with occlusion (compared with healing without occlusion) include:
      • a.
        Reduction in inflammatory cytokines.
      • b.
        Reduction in scar formation.
      • c.
        Faster healing.
      • d.
        Increased moisture.
      • e.
        All of the above.

      Topic Article

      Additional images related to this condition and the differential diagnosis may be found at: http://www.visualdx.com/visualdx/visualdx6/getZoomImage.do?moduleId=28&diagnosisId=52982&imageIndex=3&sl=c249ZGFsbGlhJmlkPTcyNjM%3D

      REFERENCES

      Questions 2 and 3 refer to the following article

        • Xu W.
        • Jia S.
        • Xie P.
        • et al.
        The expression of proinflammatory genes in epidermal keratinocytes is regulated by hydration status.
        J Invest Dermatol. 2014; 134: 1044-1055