QUESTIONS
- 1.What is your diagnosis?
- a.Systemic sclerosis.
- b.Graft-versus-host disease.
- c.Scleredema.
- d.Morphea.
- e.Nephrogenic systemic fibrosis.
- a.
- 2.Benefits of skin-specific ablation of mast cells (compared with other models of mast-cell elimination) include the following (choose all that apply):
- a.Superior removal of all mast cells.
- b.Clarification of contradictory results of other mast-cell models.
- c.Ability to examine skin-specific effects of mast cells.
- d.Allows examination of mast-cell trafficking.
- e.All of the above.
- a.
- 3.Based on the above work, which is true about the role of mast cells in repair?
- a.Critical for wound healing.
- b.Possibly needed but redundancy exists.
- c.Without mast cells scarring is prevented.
- d.Without mast cells scarring is increased.
- e.None of the above.
- a.
TOPIC ARTICLE
Answers are available as supplementary material at http://dx.doi.org/10.1038/jid.2014.214.
Additional images related to this condition and the differential diagnosis may be found at: http://info.visualdx.com/l/11412/2014-05-02/vx3yw
- Supplementary Information 1
Questions 2 and 3 refer to the following article:
- Genetic ablation of mast cells redefines the role of mast cells in skin wound healing and bleomycin-induced fibrosis.J Invest Dermatol. 2014; 134: 2005-2015
Article info
Footnotes
JID and Logical Images, Inc., have cooperated to offer the JID VisualDx Quiz, incorporating diagnostic images from VisualDx’s vast database. Questions relate to the image as well as to selected articles in JID, which are listed after the questions. Answers will be posted as supplementary material. We hope you enjoy this challenge.
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© 2014 The Society for Investigative Dermatology, Inc. Published by Elsevier Inc.
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