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JID VisualDx Quiz: April 2015

      Questions

      • 1.
        What is your diagnosis?
        • a.
          Vitiligo.
        • b.
          Piebaldism.
        • c.
          Pinta.
        • d.
          Chemical leukoderma.
        • e.
          Albinism.
      • 2.
        Which of the following is the most likely reason that intent-to-treat analyses are preferred over per-protocol analysis?
        • a.
          More likely to represent a real-life experience.
        • b.
          More likely to control for bias.
        • c.
          More likely to have planned for sample size.
        • d.
          More likely to show a significant difference.
        • e.
          More likely to study a population that will use treatment in clinic.
      • 3.
        On what was the twice-weekly dosing schedule for tacrolimus based?
        • a.
          Previous studies performed in patients with atopic dermatitis.
        • b.
          Previous studies performed in patients with vitiligo.
        • c.
          Patient convenience.
        • d.
          Searching for lowest possible effective dose.
        • e.
          All of the above.

      TOPIC ARTICLE

      Questions 2 and 3 refer to the following article:
      Cavalié M, Ezzedine K, Fontas E et al. (2015) Maintenance therapy of adult vitiligo with 0.1% tacrolimus ointment: a randomized, double blind, placebo-controlled study. J Invest Dermatol 135:970–4