October 2017 - Vol 137 No 10

A schematic diagram depicting the position of KtyI and KtyII loci relative to DAPI-dense.

In the absence of transcription factor p63 (p63_/_), keratin type I (KtyI) and keratin type II (KytII) loci are found in close proximity to transcriptionally inactive chromocenters, rather than active RNA polymerase II (RNAPIIS2p), as in wild type (WT) keratinocytes. For details, see the article by Rapisara and coworkers on page 2157.