December 2017 - Vol 137 No 12

Photographs of representative H and E images showing eosinophils in the dermis (inset) and immunostaining with antibodies against CD11c.

Topical co-application of the synthetic RORa/b inverse agonist SR1001 and MC903 (calcipotriol hydrate) to C57BL/6 mouse ear skin blunted the atopic dermatitis-like inflammation induced by MC903. TPA-induced irritant dermatitis was similarly inhibited by SR1001. See the article by Das and coworkers on page 2523 for details.