November 2019 — Vol 139 No 11

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Sola-Carvajal and colleagues report that a mutant progerinprotein that is found in patients with Hutchinson-Gilford progeria syndrome regulates basal cell division symmetry intransgenic mouse skin. This photomicrograph nicely illustrates parallel (symmetric) and perpendicular (asymmetric) cell division as manifested by the orientation of mitotic spindles inkeratin 5-expressing basal cells. See the report on page 2272 for details.