June 2020 — Vol 140 No 6

Li and colleagues implicate diminished ten-eleven translocation (TET) methylcytosine dioxygenase expression and loss of the DNA hydroxymethylcytosine mark 5-hydroxymethylcytosine (5-hmC) in keratinocyte stem cell dysregulation and psoriasiform changes in patients with psoriasis and imiquimod-treated mice.

Li and colleagues implicate diminished ten-eleven translocation (TET) methylcytosine dioxygenase expression and loss of the DNA hydroxymethylcytosine mark 5-hydroxymethylcytosine (5-hmC) in keratinocyte stem cell dysregulation and psoriasiform changes in patients with psoriasis and imiquimod-treated mice. See the Article (pages 1266-1275) for the complete story.

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