Pemphigus & Pemphigoid
- The Pemphigus Disease Area Index (PDAI) and Autoimmune Bullous Skin Disorder Intensity-Score (ABSIS) scores have been proposed to provide an objective measure of pemphigus activity. These scores have been evaluated only on already treated patients mainly with mild to moderate activity. The objective was to assess the interrater reliability of ABSIS and PDAI scores and their correlation with other severity markers in a large international study. Consecutive patients with newly diagnosed pemphigus were enrolled in 31 centers.
- The incidence of pemphigus varies from 0.5 to 34 cases/million inhabitants/year, with the highest incidence rates in Brazil (Hans-Filho et al., 1996; Ishii et al., 2008; Langan et al., 2008; Meyer and Misery, 2010). Additionally, although the prognosis of pemphigus patients is considered good in the literature, recent findings reported unusually high mortality rates (Almugairen et al., 2013; Langan et al., 2008).