Advertisement
Journal of Investigative Dermatology Home

September 16, 2021

CD39+ Fibroblasts Enhance Myofibroblast Activation by Promoting IL-11 Secretion in Hypertrophic Scars

  • Xin Huang,
  • Shuchen Gu,
  • Caiyue Liu,
  • ...
  • Danyang Zhao,
  • Qingfeng Li,
  • Tao Zan
Published online: September 16, 2021

Cytosolic DNA‒Mediated STING-Dependent Inflammation Contributes to the Progression of Psoriasis

  • Yongsheng Yu,
  • Xiaochun Xue,
  • Wendong Tang,
  • Li Su,
  • Lei Zhang,
  • Yuefan Zhang
Published online: September 16, 2021

T-Cell‒Mediated Autoimmunity: Mechanisms and Future Directions

  • Peter Seiringer,
  • Natalie Garzorz-Stark,
  • Kilian Eyerich
Published online: September 16, 2021

Targeting the Human βc Receptor Inhibits Contact Dermatitis in a Transgenic Mouse Model

  • Kwok Ho Yip,
  • Duncan McKenzie,
  • Hayley S. Ramshaw,
  • ...
  • Timothy R. Hercus,
  • Angel F. Lopez,
  • Damon J. Tumes
Published online: September 16, 2021

GWAS Identifies Three Susceptibility Loci for Trichilemmal Cysts

  • Ahmed Yousaf,
  • Michael S. Kolodney
Published online: September 16, 2021

September 15, 2021

Single-Cell Analysis Reveals Major Histocompatibility Complex II‒Expressing Keratinocytes in Pressure Ulcers with Worse Healing Outcomes

  • Dongqing Li,
  • Shangli Cheng,
  • Yu Pei,
  • ...
  • Liv Eidsmo,
  • Qiaolin Deng,
  • Ning Xu Landén
Published online: September 15, 2021
Open Access

Loss of AIRE-Mediated Immune Tolerance and the Skin

  • Pärt Peterson,
  • Kai Kisand,
  • Nicolas Kluger,
  • Annamari Ranki
Published online: September 15, 2021

Tofacitinib Suppresses IL-10/IL-10R Signaling and Modulates Host Defense Responses in Human Macrophages

  • Kristin Knoke,
  • Robert R. Rongisch,
  • Katarzyna M. Grzes,
  • ...
  • Edward J. Pearce,
  • David M. Kofler,
  • Mario Fabri
Published online: September 15, 2021

Molecular and cellular characterization of pyoderma gangrenosum: Implications for the use of gene expression

  • Alex G. Ortega-Loayza,
  • Marcia A. Friedman,
  • Ashley M. Reese,
  • ...
  • Lina Gao,
  • Suzanne S. Fei,
  • James T. Rosenbaum
Published online: September 15, 2021

Positive Allosteric Modulation of A2AR Alters Immune Cell Responses and Ameliorates Psoriasis-Like Dermatitis in Mice

  • Ajith Welihinda,
  • Puja Ravikumar,
  • Manmeet Kaur,
  • ...
  • Shruti Yadav,
  • Gyeong Jin Kang,
  • Edward Amento
Published online: September 15, 2021
Open Access

September 14, 2021

Transcriptomic Repositioning Analysis Identifies mTOR Inhibitor as Potential Therapy for Epidermolysis Bullosa Simplex

  • Gun Ho Lee,
  • Ramrada Lekwuttikarn,
  • Elidia Tafoya,
  • Monica Martin,
  • Kavita Y. Sarin,
  • Joyce M. Teng
Published online: September 14, 2021

Oncostatin M Improves Cutaneous Wound Re-Epithelialization and Is Deficient under Diabetic Conditions

  • Amitava Das,
  • Amit K. Madeshiya,
  • Nirupam Biswas,
  • ...
  • Savita Khanna,
  • Chandan K. Sen,
  • Sashwati Roy
Published online: September 14, 2021

Itch in Lichen Simplex Chronicus Is Associated with Localized Small Fiber Neuropathy

  • Mauricio Sandoval,
  • Julio Parra,
  • Mauricio Reyna-Jeldes,
  • ...
  • Claudio Coddou,
  • David L.H. Bennett,
  • Margarita Calvo
Published online: September 14, 2021

September 10, 2021

IL-10 Dysregulation Underlies Chemokine Insufficiency, Delayed Macrophage Response, and Impaired Healing in Diabetic Wound

  • Ruchi Roy,
  • Janet Zayas,
  • Mohamed F. Mohamed,
  • ...
  • Timothy M. Kuzel,
  • Jochen Reiser,
  • Sasha H. Shafikhani
Published online: September 10, 2021

September 6, 2021

Activin A Sustains the Metastatic Phenotype of Tumor-Associated Macrophages and Is a Prognostic Marker in Human Cutaneous Melanoma

  • Alba Gutiérrez-Seijo,
  • Elena García-Martínez,
  • Celia Barrio-Alonso,
  • ...
  • José Antonio Avilés-Izquierdo,
  • Paloma Sánchez-Mateos,
  • Rafael Samaniego
Published online: September 06, 2021

September 1, 2021

Genomic progression of precancerous actinic keratosis to squamous cell carcinoma

  • Yoon-Seob Kim,
  • Sun Shin,
  • Seung-Hyun Jung,
  • ...
  • Gyeong Sin Park,
  • Sug Hyung Lee,
  • Yeun-Jun Chung
Published online: September 01, 2021
Open Access

August 31, 2021

Immunocompromised Patients with Therapy-Refractory Chronic Skin Diseases Show Reactivation of Latent Epstein‒Barr Virus and Cytomegalovirus Infection

  • Philipp Speth,
  • Manja Jargosch,
  • Peter Seiringer,
  • ...
  • Tilo Biedermann,
  • Stefanie Eyerich,
  • Natalie Garzorz-Stark
Published online: August 31, 2021

The Skin's Barrier: A Cryo-EM Based Overview of its Architecture and Stepwise Formation

  • Lars Norlén,
  • Magnus Lundborg,
  • Christian Wennberg,
  • Ali Narangifard,
  • Bertil Daneholt
Published online: August 31, 2021
Open Access

August 29, 2021

Viral Status Predicts the Patterns of Genome Methylation and Decitabine Response in Merkel Cell Carcinoma

  • Paul W. Harms,
  • Monique E. Verhaegen,
  • Josh N. Vo,
  • ...
  • Vincent T. Ma,
  • Andrzej A. Dlugosz,
  • Arul M. Chinnaiyan
Published online: August 29, 2021

August 27, 2021

Role of Exosomes in Dermal Wound Healing: A Systematic Review

  • Anesh Prasai,
  • Jayson W. Jay,
  • Daniel Jupiter,
  • Steven E. Wolf,
  • Amina El Ayadi
Published online: August 27, 2021

August 26, 2021

Interaction of galectin-7 with HMGCS1 in vitro may facilitate cholesterol deposition in cultured keratinocytes

  • Norihiro Fujimoto,
  • Minoru Akiyama,
  • Yasushi Satoh,
  • Shingo Tajima
Published online: August 26, 2021

August 24, 2021

B Lymphocytes Accumulate and Proliferate in Human Skin at Sites of Cutaneous Antigen Challenge

  • Isioma U. Egbuniwe,
  • Robert J. Harris,
  • Mano Nakamura,
  • ...
  • Arne N. Akbar,
  • Sophia N. Karagiannis,
  • Katie E. Lacy
Published online: August 24, 2021
Open Access

August 18, 2021

Coexpression of MTH1 and PMS2 Is Associated with Advanced Disease and Disease Progression after Therapy in Melanoma

  • Ishani Das,
  • Rainer Tuominen,
  • Thomas Helleday,
  • Johan Hansson,
  • Ulrika Warpman Berglund,
  • Suzanne Egyházi Brage
Published online: August 18, 2021
Open Access

August 13, 2021

Photosensitivity and cGAS-dependent type I IFN activation in lupus patients with TREX1 deficiency

  • Nicole Berndt,
  • Christine Wolf,
  • Kristina Fischer,
  • ...
  • Osvaldo Chara,
  • Min Ae Lee-Kirsch,
  • Claudia Günther
Published online: August 13, 2021

August 5, 2021

Altered Skin and Gut Microbiome in Hidradenitis Suppurativa

  • S. McCarthy,
  • M. Barrett,
  • S. Kirthi,
  • ...
  • M. Murphy,
  • F. Shanahan,
  • P.W. O’Toole
Published online: August 05, 2021

IFN-κ Is a Rheostat for Development of Psoriasiform Inflammation

  • Mehrnaz Gharaee-Kermani,
  • Shannon N. Estadt,
  • Lam C. Tsoi,
  • ...
  • Nicole L. Ward,
  • Johann E. Gudjonsson,
  • J. Michelle Kahlenberg
Published online: August 05, 2021

August 4, 2021

MC1R Functions, Expression, and Implications for Targeted Therapy

  • Stefania Guida,
  • Gabriella Guida,
  • Colin Ronald Goding
Published online: August 04, 2021

August 3, 2021

Sex Bias and Autoimmune Diseases

  • Enze Xing,
  • Allison C. Billi,
  • Johann E. Gudjonsson
Published online: August 03, 2021

The Evolution of Acquired Resistance to BRAFV600E kinase inhibitor Is Sustained by IGF1-Driven Tumor Vascular Remodeling

  • Guangchao Xu,
  • Ya Luo,
  • Wenshuang Wu,
  • ...
  • Jianping Hu,
  • Jing Jing,
  • Hubing Shi
Published online: August 03, 2021
Open Access

LPCAT1 Promotes Cutaneous Squamous Cell Carcinoma via EGFR-Mediated Protein Kinase B/p38MAPK Signaling Pathways

  • Yingjian Huang,
  • Yuqian Wang,
  • Yan Wang,
  • ...
  • Meng Liu,
  • Muhammad Ahsan Bilal,
  • Yan Zheng
Published online: August 03, 2021

Epigenetic Regulation of Apoptosis in Cutaneous T-Cell Lymphoma: Implications for Therapy with Methotrexate, Jak Inhibitors, and Resveratrol

  • Minakshi Nihal,
  • Jianqiang Wu,
  • Connor J. Stonesifer,
  • ...
  • Larisa Geskin,
  • Alain H. Rook,
  • Gary S. Wood
Published online: August 03, 2021

August 2, 2021

Differences in Psychometric Properties of Clinician- and Patient-Reported Outcome Measures for Atopic Dermatitis by Race and Skin Tone: A Systematic Review

  • Trisha Kaundinya,
  • Uros Rakita,
  • Armaan Guraya,
  • ...
  • Jacob P. Thyssen,
  • Andrew Alexis,
  • Jonathan I. Silverberg
Published online: August 02, 2021

Naturally Occurring Telomerase-Specific CD4 T-Cell Immunity in Melanoma

  • Charlée Nardin,
  • Caroline Laheurte,
  • Eve Puzenat,
  • ...
  • Yann Godet,
  • François Aubin,
  • Olivier Adotevi
Published online: August 02, 2021

IL-22 Downregulates Peptidylarginine Deiminase-1 in Human Keratinocytes: Adding Another Piece to the IL-22 Puzzle in Epidermal Barrier Formation

  • Avinash Padhi,
  • Ankit Srivastava,
  • Abarajitha Ramesh,
  • ...
  • Liv Eidsmo,
  • Peter Bergman,
  • Josefin Lysell
Published online: August 02, 2021

Differential Pathomechanisms of Desmoglein 1 Transmembrane Domain Mutations in Skin Disease

  • Stephanie E. Zimmer,
  • Takuya Takeichi,
  • Daniel E. Conway,
  • ...
  • Yasushi Suga,
  • Masashi Akiyama,
  • Andrew P. Kowalczyk
Published online: August 02, 2021

Increased Activation of Innate Immunity and Pro-Apoptotic CXCR3B in Normal-Appearing Skin on the Lesional Site of Patients with Segmental Vitiligo

  • Thierry Passeron,
  • Valentina E.A. Malmqvst,
  • Hanene Bzioueche,
  • Sandrine Marchetti,
  • Stephane Rocchi,
  • Meri K. Tulic
Published online: August 02, 2021

ZFP36 family members regulate the pro-inflammatory features of psoriatic dermal fibroblasts

  • Chiara Angiolilli,
  • Emmerik F.A. Leijten,
  • Cornelis P.J. Bekker,
  • ...
  • Femke van Wijk,
  • Timothy R.D.J. Radstake,
  • Jorg van Loosdregt
Published online: August 02, 2021
Open Access

July 27, 2021

July 23, 2021

Lack of Significant Association between Sex Hormone Concentrations and Atopic Dermatitis in Adolescents and Adults in Two Population-Based Studies

  • Hanna Kische,
  • Anke Hannemann,
  • Catharina Voss,
  • ...
  • Lars Pieper,
  • Katja Beesdo-Baum,
  • Andreas Arnold
Published online: July 23, 2021
Advertisement