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- Letter to the EditorOpen Archive
Association between Body Mass Index, C-Reactive Protein Levels, and Melanoma Patient Outcomes
Journal of Investigative DermatologyVol. 137Issue 8p1792–1795Published online: April 22, 2017- Shenying Fang
- Yuling Wang
- Yifang Dang
- Andrew Gagel
- Merrick I. Ross
- Jeffrey E. Gershenwald
- and others
Cited in Scopus: 31Obesity is a known risk factor for cancer development (Arnold et al., 2016; Basen-Engquist and Chang, 2011; Renehan et al., 2015) and death (Calle et al., 2003). Obesity has been associated with an increased risk of developing melanoma in men (Sergentanis et al., 2013) and with thicker primary melanomas (Skowron et al., 2015). The inflammatory adipokine leptin promotes melanoma progression in mice (Amjadi et al., 2011; Brandon et al., 2009; Gogas et al., 2008); elevated leptin levels may predict melanoma sentinel node metastasis (Oba et al., 2016).