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- Original Article Tumor BiologyOpen Archive
A Model to Predict the Risk of Keratinocyte Carcinomas
Journal of Investigative DermatologyVol. 136Issue 6p1247–1254Published online: February 21, 2016- David C. Whiteman
- Bridie S. Thompson
- Aaron P. Thrift
- Maria-Celia Hughes
- Chiho Muranushi
- Rachel E. Neale
- and others
Cited in Scopus: 26Basal cell and squamous cell carcinomas of the skin are the commonest cancers in humans, yet no validated tools exist to estimate future risks of developing keratinocyte carcinomas. To develop a prediction tool, we used baseline data from a prospective cohort study (n = 38,726) in Queensland, Australia, and used data linkage to capture all surgically excised keratinocyte carcinomas arising within the cohort. Predictive factors were identified through stepwise logistic regression models. In secondary analyses, we derived separate models within strata of prior skin cancer history, age, and sex.