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Melanoma
2 Results
- Review Article
Mental Health and Illness
Primary Care: Clinics in Office PracticeVol. 48Issue 1p131–145Published online: December 3, 2020- Kim S. Griswold
- Dianne M. Loomis
- Patricia A. Pastore
Cited in Scopus: 1Circumstances forcing individuals and families to flee set the stage for disruptions in mental health and forge resilience. Individual characteristics and conditions premigration, perimigration, and postmigration influence health, mental health, care-seeking behavior, and stages of well-being and successful resettlement. Primary care providers have strategies to promote mental well-being, including focusing on resilience and social determinants of health. Integrated or collaborative care models are ideal for delivering optimum care for refugee and immigrant communities. Connecting primary and behavioral care promotes a team approach; provides comprehensive, whole-person care; and relies on participation of patients and families. - ReviewOpen Archive
Replenishing Regulatory T Cells to Halt Depigmentation in Vitiligo
Journal of Investigative Dermatology Symposium ProceedingsVol. 18Issue 2S38–S45Published in issue: October, 2017- I. Caroline Le Poole
- Shikhar Mehrotra
Cited in Scopus: 34Vitiligo is a cutaneous autoimmune disease, especially devastating to patients with darker skin tones because of the contrast between unaffected and lesional skin. We studied immune cells infiltrating vitiligo skin and found very few regulatory T cells (Tregs). Vitiligo was not associated with a reduced frequency or function of circulating Tregs. To manipulate Treg function, we used mouse models expressing melanocyte-reactive TCRs, following changes in pelage color. We also isolated splenocytes to measure Treg function and evaluated cutaneous Treg abundance.