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      Recent Highlights in Psoriasis Research

      Journal of Investigative Dermatology
      Vol. 137Issue 3p550–556Published online: January 4, 2017
      • Samuel T. Hwang
      • Tamar Nijsten
      • James T. Elder
      Cited in Scopus: 46
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        This article highlights recent advances in the immunology, epidemiology, and genetics/genomics of psoriasis. Advances sometimes generate more questions, and this article makes an attempt to point out where controversies might exist in the literature. Many of the articles mentioned were published in the Journal of Investigative Dermatology, but many articles from the broader scientific literature are also cited, to provide context and to add further validity for some of these key findings. Among the themes we explore are the identification of antigens in psoriasis, the co-morbidities of psoriasis, and novel integrative approaches to genome-wide association studies.
      • Review
        Open Archive

        microRNAs in Psoriasis

        Journal of Investigative Dermatology
        Vol. 136Issue 2p365–371Published in issue: February, 2016
        • Jason E. Hawkes
        • Giang Huong Nguyen
        • Mayumi Fujita
        • Scott R. Florell
        • Kristina Callis Duffin
        • Gerald G. Krueger
        • and others
        Cited in Scopus: 91
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          Psoriasis is a chronic inflammatory skin condition resulting from a complex interplay among the immune system, keratinocytes, susceptibility genes, and environmental factors. However, the pathogenesis of psoriasis is not completely elucidated. microRNAs represent a promising class of small, noncoding RNA molecules that function to regulate gene expression. Although microRNA research in psoriasis and dermatology is still relatively new, evidence is rapidly accumulating for the role of microRNAs in the pathogenesis of psoriasis and other chronic inflammatory conditions.
          microRNAs in Psoriasis
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